EXPRESS: Differentiation of the 50B11 dorsal root cells into NGF and GDNF responsive nociceptor subtypes
The embryonic rat dorsal root ganglion (DRG) neuron-derived 50B11 cell line is a promising sensory neuron mannequin expressing markers attribute of NGF and GDNF-dependent C-fibre nociceptors. Whether or not these cells have the capability to turn into distinct nociceptive subtypes primarily based on NGF- or GDNF-dependence has not been investigated.
Right here we present that by augmenting forskolin (FSK) and progress issue supplementation with NGF or GDNF, 50B11 cultures could be pushed to accumulate differential practical responses to frequent nociceptive agonists capsaicin and ATP respectively. As well as, to earlier research, we additionally show {that a} differentiated neuronal phenotype could be maintained for as much as 7 days.
Western blot evaluation of nociceptive marker proteins additional demonstrates that the 50B11 cells partially recapitulate the practical phenotypes of classical NGF-dependent (peptidergic) and GDNF-dependent (non-peptidergic) neuronal subtypes described in DRGs. Additional, 50B11 cells differentiated with NGF/FSK, however not GDNF/FSK, present sensitization to acute prostaglandin E2 therapy.
Lastly, RNA-Seq evaluation confirms that differentiation with NGF/FSK or GDNF/FSK produces two 50B11 cell subtypes with distinct transcriptome expression profiles. Gene ontology comparability of the 2 subtypes of differentiated 50B11 cells to rodent DRG neurons research exhibits vital overlap in matching or partially matching classes.
This transcriptomic evaluation will help future suitability evaluation of the 50B11 cells as a high-throughput nociceptor mannequin for a broad vary of experimental purposes. In conclusion, this examine exhibits that the 50B11 cell line is able to partially recapitulating options of two distinct forms of embryonic NGF and GDNF-dependent nociceptor-like cells.
A human related combination of persistent natural pollution (POPs) and perfluorooctane sulfonic acid (PFOS) improve nerve progress issue (NGF)-induced neurite outgrowth in PC12 cells
Disruption of neurite outgrowth is a marker for neurotoxicity. Persistent natural pollution (POPs) are potential developmental neurotoxicants. We investigated their impact on neurite outgrowth in PC12 rat pheochromocytoma cells, in absence or presence of nerve progress issue (NGF), an inducer of neuronal differentiation. Cells had been uncovered for 72 h to an outlined combination of POPs with chemical composition and concentrations primarily based on blood ranges within the Scandinavian inhabitants.
We additionally evaluated perfluorooctane sulfonic acid (PFOS) alone, probably the most ample compound within the POP combination. Solely excessive concentrations of POP combination lowered tetrazolium salt (MTT) conversion. Excessive-content evaluation confirmed a lower in cell quantity, however no modifications for nuclear and mitochondrial mobile well being parameters.
Sturdy glutathione ranges had been noticed in NGF-differentiated cells. Stay imaging, utilizing the IncuCyte ZOOM platform indicated ongoing cell proliferation over time, however slower in presence of NGF. The pollution didn’t inhibit neuritogenesis, however somewhat elevated NGF-induced neurite size. PFOS induced neurite outgrowth to about 50% of the extent seen with the POP combination. Neither the POP combination nor PFOS affected neurite size within the absence of NGF. Our observations point out that lifelike advanced mixtures of environmental pollution can have an effect on neuronal connectivity by way of NGF-induced neurite outgrowth.
The biased ligands NGF and NT-Three differentially stabilize Trk-A dimers
Trk-A is a receptor tyrosine kinase (RTK) which performs an important position within the growth and functioning of the nervous system. Trk-A is expressed in neurons and alerts in response to 2 ligands, NGF and NT-3, with very totally different practical penalties. Thus, NGF and NT-Three are “biased” ligands for Trk-A. Because it has been hypothesized that biased RTK ligands induce differential stabilization of RTK dimers, right here we search to check this speculation for NGF and NT-3.
Particularly, we use Förster Resonance Power Switch (FRET) and Fluorescence Depth Fluctuation (FIF) spectroscopy to evaluate the energy of Trk-A interactions and Trk-A oligomer measurement within the presence of the 2 ligands. Whereas the distinction in Trk-A conduct in response to the 2 ligands has been beforehand attributed to variations of their binding to Trk-A within the endosomes at low pH, right here we additional present variations within the stabilities of the NGF and NT-Three certain Trk-A dimers within the plasma membrane and at impartial pH. We talk about the organic significance of those new findings and their implications for the design of Trk-A ligands with novel functionalities.
Results of NGF and BDNF on chondrocytes: a microarray evaluation
Osteoarthritis (OA) represents an inflammation-driven harm of articular tissues, progressively resulting in structural and practical joint impairment. The principle symptom of OA is ache. Though it has been nicely established that OA represents a complete joint illness, the supply of ache stays to be clarified. These days, it has been nicely established that neurotrophines expression is obvious in joints affected by OA. As well as, elevated NGF ranges are discovered within the synovial fluid of sufferers with inflammatory or degenerative rheumatic ailments, together with OA, rheumatoid arthritis and spondylarthritis.
Rising evidences point out that blocking NGF signaling utilizing an anti NGF agent (i.e. tanezumab) offers efficient ache aid. This examine analyzed the consequences of NGF and BDNF on cultured human chondrocytes by evaluating and their results on chondrogenesis, chondrocyte differentiation and cartilage degeneration by a microarray evaluation. The entire transcriptome evaluation carried out on this examine highlighted how NGF and BDNF may be capable to induce a proinflammatory response in human chondrocytes. Furthermore, NGF and BDNF remedies appears to have the ability to induce the activation of a number of genes concerned within the OA pathogenesis as IL17AR, HLA-DRB1, GDF-15, NR1D1, MCF2L and TGF-Beta.
Potential position of NGF, BDNF and their receptors in Oligodendrocytes differentiation from neural stem cell – an in-vitro examine
Neural stem cells (NSCs) or neuronal progenitor cells (NPCs) are cells able to differentiating into oligodendrocytes, myelin-forming cells which have the potential of remyelination. Mind-derived neurotrophic issue (BDNF) and Nerve progress issue (NGF) are two neurotrophic components which were studied to stimulate NSC differentiation thus taking part in a job in MS (A number of Sclerosis) pathogenesis and a number of other different demyelinating issues. Whereas a number of research have demonstrated the proliferative and protecting capabilities of those neurotrophic components, their mobile and molecular features are nonetheless not nicely understood.
Thus within the current examine we concentrate on understanding the position of those neurotrophins (BDNF and NGF) in oligodendrogenesis from NSCs. Each neurotrophic components have proven to advertise NSC proliferation and NSC differentiation significantly into oligodendroglial lineage in a dose dependent trend. Additional, to determine the position of those neurotrophins in NSC differentiation, we’ve got employed pharmacological inhibitors for TrkA and TrkB receptors in NSCs.
Using these inhibitors suppressed NSC differentiation into oligodendrocytes together with the down-regulation of phosphorylated ERK suggesting energetic involvement of ERK in functioning of those neurotrophins.
 NGF Polyclonal Antibody |
|
41239-50ul |
SAB |
50ul |
EUR 224.4 |
NGF Polyclonal Antibody |
|
ABP53296-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
|
|
Description: A polyclonal antibody for detection of NGF from Human. This NGF antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human NGF |
NGF Polyclonal Antibody |
|
ABP53296-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
|
|
Description: A polyclonal antibody for detection of NGF from Human. This NGF antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human NGF |
NGF Polyclonal Antibody |
|
ABP53296-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
|
|
Description: A polyclonal antibody for detection of NGF from Human. This NGF antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human NGF |
NGF Polyclonal Antibody |
|
ABP51959-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
|
|
Description: A polyclonal antibody for detection of NGF from Human, Mouse, Rat. This NGF antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human NGF |
NGF Polyclonal Antibody |
|
ABP51959-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
|
|
Description: A polyclonal antibody for detection of NGF from Human, Mouse, Rat. This NGF antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human NGF |
NGF Polyclonal Antibody |
|
ABP51959-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
|
|
Description: A polyclonal antibody for detection of NGF from Human, Mouse, Rat. This NGF antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human NGF |
 NGF polyclonal antibody |
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BS79861 |
Bioworld Biotech |
50ul |
EUR 358 |
|
|
|
Description: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
NGF polyclonal antibody |
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BS79891 |
Bioworld Biotech |
50ul |
EUR 358 |
|
|
|
Description: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
 NGF polyclonal antibody |
|
BS90942 |
Bioworld Biotech |
50ul |
EUR 398 |
|
|
|
Description: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
NGF polyclonal antibody |
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BS90943 |
Bioworld Biotech |
50ul |
EUR 398 |
|
|
|
Description: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
NGF Polyclonal Antibody |
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E-AB-93105-120uL |
Elabscience Biotech |
120uL |
EUR 320 |
|
|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-93105-200uL |
Elabscience Biotech |
200uL |
EUR 530 |
|
|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-93105-60uL |
Elabscience Biotech |
60uL |
EUR 200 |
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|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-93105-each |
Elabscience Biotech |
each |
Ask for price |
|
|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-10487-120uL |
Elabscience Biotech |
120uL |
EUR 240 |
|
|
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Description: Unconjugated |
NGF Polyclonal Antibody |
|
E-AB-10487-200uL |
Elabscience Biotech |
200uL |
EUR 399 |
|
|
|
Description: Unconjugated |
NGF Polyclonal Antibody |
|
E-AB-10487-20uL |
Elabscience Biotech |
20uL |
EUR 73 |
|
|
|
Description: Unconjugated |
NGF Polyclonal Antibody |
|
E-AB-10487-60uL |
Elabscience Biotech |
60uL |
EUR 143 |
|
|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-14245-120uL |
Elabscience Biotech |
120uL |
EUR 240 |
|
|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-14245-200uL |
Elabscience Biotech |
200uL |
EUR 399 |
|
|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-14245-20uL |
Elabscience Biotech |
20uL |
EUR 73 |
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|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-14245-60uL |
Elabscience Biotech |
60uL |
EUR 143 |
|
|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-32239-120uL |
Elabscience Biotech |
120uL |
EUR 240 |
|
|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-32239-200uL |
Elabscience Biotech |
200uL |
EUR 399 |
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|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-32239-20uL |
Elabscience Biotech |
20uL |
EUR 73 |
|
|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-32239-60uL |
Elabscience Biotech |
60uL |
EUR 143 |
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|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-40051-120uL |
Elabscience Biotech |
120uL |
EUR 230 |
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|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-40051-200uL |
Elabscience Biotech |
200uL |
EUR 380 |
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|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-40051-20uL |
Elabscience Biotech |
20uL |
EUR 65 |
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|
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Description: Unconjugated |
NGF Polyclonal Antibody |
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E-AB-40051-60uL |
Elabscience Biotech |
60uL |
EUR 125 |
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|
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Description: Unconjugated |
NGF polyclonal antibody |
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BS6454 |
Bioworld Biotech |
50 ul |
EUR 358 |
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|
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Description: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
NGF polyclonal antibody |
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BZ16118 |
Bioworld Biotech |
50ul |
EUR 358 |
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|
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Description: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
NGF polyclonal antibody |
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BZ16467 |
Bioworld Biotech |
50ul |
EUR 358 |
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|
|
Description: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
NGF Polyclonal Antibody |
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BT-AP06007-100ul |
Jiaxing Korain Biotech Ltd (BT Labs) |
100ul |
Ask for price |
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|
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Description: NGF is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. Nerve growth factorp has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in NGF have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
BT-AP06007-20ul |
Jiaxing Korain Biotech Ltd (BT Labs) |
20ul |
Ask for price |
|
|
|
Description: NGF is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. Nerve growth factorp has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in NGF have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
BT-AP06007-50ul |
Jiaxing Korain Biotech Ltd (BT Labs) |
50ul |
Ask for price |
|
|
|
Description: NGF is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. Nerve growth factorp has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in NGF have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
BT-AP06008-100ul |
Jiaxing Korain Biotech Ltd (BT Labs) |
100ul |
Ask for price |
|
|
|
Description: NGF is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. Nerve growth factorp has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in NGF have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
BT-AP06008-20ul |
Jiaxing Korain Biotech Ltd (BT Labs) |
20ul |
Ask for price |
|
|
|
Description: NGF is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. Nerve growth factorp has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in NGF have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
BT-AP06008-50ul |
Jiaxing Korain Biotech Ltd (BT Labs) |
50ul |
Ask for price |
|
|
|
Description: NGF is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. Nerve growth factorp has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in NGF have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
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MBS125020-002mL |
MyBiosource |
0.02mL |
EUR 200 |
NGF Polyclonal Antibody |
|
MBS125020-005mL |
MyBiosource |
0.05mL |
EUR 255 |
NGF Polyclonal Antibody |
|
MBS125020-01mL |
MyBiosource |
0.1mL |
EUR 345 |
NGF Polyclonal Antibody |
|
MBS125020-02mL |
MyBiosource |
0.2mL |
EUR 545 |
NGF Polyclonal Antibody |
|
MBS125020-5x02mL |
MyBiosource |
5x0.2mL |
EUR 2265 |
NGF Polyclonal Antibody |
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JOT-AP06007-100ul |
Jotbody |
100ul |
EUR 220 |
|
|
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Description: Human |
NGF Polyclonal Antibody |
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JOT-AP06007-50ul |
Jotbody |
50ul |
EUR 144 |
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|
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Description: Human |
NGF Polyclonal Antibody |
|
JOT-AP06008-100ul |
Jotbody |
100ul |
EUR 220 |
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|
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Description: Human;Mouse;Rat |
NGF Polyclonal Antibody |
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JOT-AP06008-50ul |
Jotbody |
50ul |
EUR 144 |
|
|
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Description: Human;Mouse;Rat |
NGF Polyclonal Antibody |
|
E041239 |
EnoGene |
100μg/100μl |
EUR 255 |
|
Description: Available in various conjugation types. |
NGF Polyclonal Antibody |
|
E041931 |
EnoGene |
100μg/100μl |
EUR 255 |
|
Description: Available in various conjugation types. |
NGF Polyclonal Antibody |
|
E20-75565 |
EnoGene |
100ug |
EUR 225 |
|
Description: Available in various conjugation types. |
NGF Polyclonal Antibody |
|
E44H02901 |
EnoGene |
100ul |
EUR 255 |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
NGF Polyclonal Antibody |
|
E44H07007 |
EnoGene |
100ul |
EUR 255 |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
NGF Polyclonal Antibody |
|
E20-73114 |
EnoGene |
100ug |
EUR 225 |
|
Description: Available in various conjugation types. |
NGF Polyclonal Antibody |
|
E90095A |
EnoGene |
100μg/100μl |
EUR 255 |
|
Description: Available in various conjugation types. |
NGF Polyclonal Antibody |
|
E913922 |
EnoGene |
100ul |
EUR 225 |
|
Description: Available in various conjugation types. |
NGF Polyclonal Antibody |
|
E914216 |
EnoGene |
100ul |
EUR 225 |
|
Description: Available in various conjugation types. |
NGF Polyclonal Antibody |
|
MBS2518027-002mL |
MyBiosource |
0.02mL |
EUR 135 |
NGF Polyclonal Antibody |
|
MBS2518027-006mL |
MyBiosource |
0.06mL |
EUR 190 |
NGF Polyclonal Antibody |
|
MBS2518027-012mL |
MyBiosource |
0.12mL |
EUR 265 |
NGF Polyclonal Antibody |
|
MBS2518027-02mL |
MyBiosource |
0.2mL |
EUR 415 |
NGF Polyclonal Antibody |
|
MBS2518027-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1835 |
NGF Polyclonal Antibody |
|
MBS2538871-002mL |
MyBiosource |
0.02mL |
EUR 135 |
NGF Polyclonal Antibody |
|
MBS2538871-006mL |
MyBiosource |
0.06mL |
EUR 190 |
NGF Polyclonal Antibody |
|
MBS2538871-012mL |
MyBiosource |
0.12mL |
EUR 265 |
NGF Polyclonal Antibody |
|
MBS2538871-02mL |
MyBiosource |
0.2mL |
EUR 415 |
NGF Polyclonal Antibody |
|
MBS2538871-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1835 |
NGF Polyclonal Antibody |
|
MBS2539537-002mL |
MyBiosource |
0.02mL |
EUR 140 |
NGF Polyclonal Antibody |
|
MBS2539537-006mL |
MyBiosource |
0.06mL |
EUR 180 |
NGF Polyclonal Antibody |
|
MBS2539537-012mL |
MyBiosource |
0.12mL |
EUR 260 |
NGF Polyclonal Antibody |
|
MBS2539537-02mL |
MyBiosource |
0.2mL |
EUR 405 |
NGF Polyclonal Antibody |
|
MBS2541746-002mL |
MyBiosource |
0.02mL |
EUR 130 |
NGF Polyclonal Antibody |
|
MBS2541746-006mL |
MyBiosource |
0.06mL |
EUR 175 |
NGF Polyclonal Antibody |
|
MBS2541746-012mL |
MyBiosource |
0.12mL |
EUR 255 |
NGF Polyclonal Antibody |
|
MBS2541746-02mL |
MyBiosource |
0.2mL |
EUR 380 |
NGF Polyclonal Antibody |
|
MBS2541746-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1675 |
NGF Polyclonal Antibody |
|
MBS2526117-002mL |
MyBiosource |
0.02mL |
EUR 135 |
NGF Polyclonal Antibody |
|
MBS2526117-006mL |
MyBiosource |
0.06mL |
EUR 190 |
NGF Polyclonal Antibody |
|
MBS2526117-012mL |
MyBiosource |
0.12mL |
EUR 265 |
NGF Polyclonal Antibody |
|
MBS2526117-02mL |
MyBiosource |
0.2mL |
EUR 415 |
NGF Polyclonal Antibody |
|
MBS2526117-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1835 |
NGF Polyclonal Antibody |
|
MBS9244509-01mL |
MyBiosource |
0.1mL |
EUR 415 |
NGF Polyclonal Antibody |
|
MBS9244509-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1841 |
NGF Polyclonal Antibody |
|
MBS9246181-01mL |
MyBiosource |
0.1mL |
EUR 415 |
NGF Polyclonal Antibody |
|
MBS9246181-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1841 |
NGF Polyclonal Antibody |
|
MBS9133933-002mL |
MyBiosource |
0.02mL |
EUR 200 |
NGF Polyclonal Antibody |
|
MBS9133933-005mL |
MyBiosource |
0.05mL |
EUR 255 |
NGF Polyclonal Antibody |
|
MBS9133933-01mL |
MyBiosource |
0.1mL |
EUR 345 |
NGF Polyclonal Antibody |
|
MBS9133933-02mL |
MyBiosource |
0.2mL |
EUR 545 |
NGF Polyclonal Antibody |
|
MBS9133933-5x02mL |
MyBiosource |
5x0.2mL |
EUR 2265 |
NGF Polyclonal Antibody |
|
MBS9134225-002mL |
MyBiosource |
0.02mL |
EUR 200 |
NGF Polyclonal Antibody |
|
MBS9134225-005mL |
MyBiosource |
0.05mL |
EUR 255 |
NGF Polyclonal Antibody |
|
MBS9134225-01mL |
MyBiosource |
0.1mL |
EUR 345 |
NGF Polyclonal Antibody |
|
MBS9134225-02mL |
MyBiosource |
0.2mL |
EUR 545 |
NGF Polyclonal Antibody |
|
MBS9134225-5x02mL |
MyBiosource |
5x0.2mL |
EUR 2265 |
NGF Polyclonal Antibody |
|
MBS8526546-01mg |
MyBiosource |
0.1mg |
EUR 305 |
NGF Polyclonal Antibody |
|
MBS8526546-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 465 |
NGF Polyclonal Antibody |
|
MBS8526546-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 465 |
NGF Polyclonal Antibody |
|
MBS8526546-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 465 |
NGF Polyclonal Antibody |
|
MBS8526546-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 465 |
NGF Polyclonal Antibody |
|
MBS8524095-01mg |
MyBiosource |
0.1mg |
EUR 305 |
NGF Polyclonal Antibody |
|
MBS8524095-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 465 |
NGF Polyclonal Antibody |
|
MBS8524095-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 465 |
NGF Polyclonal Antibody |
|
MBS8524095-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 465 |
NGF Polyclonal Antibody |
|
MBS8524095-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 465 |
NGF Polyclonal Antibody |
|
MBS8527312-01mg |
MyBiosource |
0.1mg |
EUR 325 |
NGF Polyclonal Antibody |
|
MBS8527312-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS8527312-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS8527312-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS8527312-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS8568907-01mL |
MyBiosource |
0.1mL |
EUR 305 |
NGF Polyclonal Antibody |
|
MBS8568907-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS8568907-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS8568907-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS8568907-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS8568628-01mL |
MyBiosource |
0.1mL |
EUR 305 |
NGF Polyclonal Antibody |
|
MBS8568628-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS8568628-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS8568628-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS8568628-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
NGF Polyclonal Antibody |
|
MBS9408290-005mL |
MyBiosource |
0.05mL |
EUR 245 |
NGF Polyclonal Antibody |
|
MBS9408290-01mL |
MyBiosource |
0.1mL |
EUR 305 |
NGF Polyclonal Antibody |
|
MBS9408290-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1230 |
NGF Polyclonal Antibody |
|
MBS9409294-005mL |
MyBiosource |
0.05mL |
EUR 245 |
NGF Polyclonal Antibody |
|
MBS9409294-01mL |
MyBiosource |
0.1mL |
EUR 305 |
NGF Polyclonal Antibody |
|
MBS9409294-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1230 |
NGF Polyclonal Antibody |
|
RD71549A-120uL |
Reddot Biotech |
120μL |
EUR 360 |
|
|
|
Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. |
NGF Polyclonal Antibody |
|
RD71549A-200uL |
Reddot Biotech |
200μL |
EUR 630 |
|
|
|
Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. |
NGF Polyclonal Antibody |
|
RD71549A-20uL |
Reddot Biotech |
20μL |
EUR 109.5 |
|
|
|
Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. |
NGF Polyclonal Antibody |
|
RD71549A-60uL |
Reddot Biotech |
60μL |
EUR 214.5 |
|
|
|
Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. |
NGF Polyclonal Antibody |
|
RD75289A-120uL |
Reddot Biotech |
120μL |
EUR 360 |
|
|
|
Description: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
RD75289A-200uL |
Reddot Biotech |
200μL |
EUR 630 |
|
|
|
Description: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
RD75289A-20uL |
Reddot Biotech |
20μL |
EUR 109.5 |
|
|
|
Description: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
RD75289A-60uL |
Reddot Biotech |
60μL |
EUR 214.5 |
|
|
|
Description: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
RD240051A-120uL |
Reddot Biotech |
120μL |
EUR 345 |
|
|
|
Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. |
NGF Polyclonal Antibody |
|
RD240051A-200uL |
Reddot Biotech |
200μL |
EUR 570 |
|
|
|
Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. |
NGF Polyclonal Antibody |
|
RD240051A-20uL |
Reddot Biotech |
20μL |
EUR 97.5 |
|
|
|
Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. |
NGF Polyclonal Antibody |
|
RD240051A-60uL |
Reddot Biotech |
60μL |
EUR 187.5 |
|
|
|
Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. |
NGF Polyclonal Antibody |
|
RD77529A-120uL |
Reddot Biotech |
120μL |
EUR 360 |
|
|
|
Description: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
RD77529A-200uL |
Reddot Biotech |
200μL |
EUR 630 |
|
|
|
Description: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
RD77529A-20uL |
Reddot Biotech |
20μL |
EUR 109.5 |
|
|
|
Description: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
RD77529A-60uL |
Reddot Biotech |
60μL |
EUR 214.5 |
|
|
|
Description: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. |
NGF Polyclonal Antibody |
|
UB-GEN-12579 |
UpingBio |
100 ul |
EUR 200 |
 polyclonal antibody) NGF (L82) polyclonal antibody |
|
BS3564 |
Bioworld Biotech |
50ul |
EUR 275 |
|
|
|
Description: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
NGF (L82) polyclonal antibody |
|
E43S3564 |
EnoGene |
100ul |
EUR 225 |
|
Description: Available in various conjugation types. |
 NGF beta polyclonal antibody |
|
BS67730 |
Bioworld Biotech |
50ul |
EUR 275 |
|
|
|
Description: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
 NGF Rabbit Polyclonal Antibody |
|
ES4295-100ul |
ELK Biotech |
100ul |
EUR 124 |
|
|
|
Description: WB, IHC, ELISA |
NGF Rabbit Polyclonal Antibody |
|
ES4295-50ul |
ELK Biotech |
50ul |
EUR 74 |
|
|
|
Description: WB, IHC, ELISA |
NGF Rabbit Polyclonal Antibody |
|
E10G23168 |
EnoGene |
100 μl |
EUR 275 |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
NGF Rabbit Polyclonal Antibody |
|
E10G23528 |
EnoGene |
100 μl |
EUR 275 |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
NGF Rabbit Polyclonal Antibody |
|
E10G07482 |
EnoGene |
100 μl |
EUR 275 |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
NGF Rabbit Polyclonal Antibody |
|
E10G00563 |
EnoGene |
100 μl |
EUR 275 |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
NGF Rabbit Polyclonal Antibody |
|
E10G03743 |
EnoGene |
100 μl |
EUR 275 |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
NGF Rabbit Polyclonal Antibody |
|
E10G10675 |
EnoGene |
100 μl |
EUR 275 |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
NGF Rabbit Polyclonal Antibody |
|
ES2958-100ul |
ELK Biotech |
100ul |
EUR 124 |
|
|
|
Description: WB, IHC, ELISA |
NGF Rabbit Polyclonal Antibody |
|
ES2958-50ul |
ELK Biotech |
50ul |
EUR 74 |
|
|
|
Description: WB, IHC, ELISA |
 Ngf Polyclonal Antibody, HRP Conjugated |
|
A52043 |
EpiGentek |
-
Ask for price
-
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-
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|
|
 NGF Polyclonal Antibody, HRP Conjugated |
|
A64863 |
EpiGentek |
-
Ask for price
-
Ask for price
-
Ask for price
|
|
 Ngf Polyclonal Antibody, FITC Conjugated |
|
A52044 |
EpiGentek |
-
Ask for price
-
Ask for price
-
Ask for price
|
|
 NGF Polyclonal Antibody, FITC Conjugated |
|
A64864 |
EpiGentek |
-
Ask for price
-
Ask for price
-
Ask for price
|
|
 Ngf Polyclonal Antibody, Biotin Conjugated |
|
A52045 |
EpiGentek |
-
Ask for price
-
Ask for price
-
Ask for price
|
|
 NGF Polyclonal Antibody, Biotin Conjugated |
|
A64865 |
EpiGentek |
-
Ask for price
-
Ask for price
-
Ask for price
|
|
Morphometric evaluation additionally revealed the essential position of each neurotrophins in oligodendrocytes growth. These findings spotlight the significance of neurotrophic components in stimulating NSC differentiation and should pave a job for future research to develop neurotrophic issue alternative therapies to realize remyelination.
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