Fabry disease-associated globotriaosylceramide induces mechanical allodynia via activation of signaling through proNGF-p75 NTR but not mature NGF-TrkA

Fabry disease-associated globotriaosylceramide induces mechanical allodynia via activation of signaling through proNGF-p75 NTR but not mature NGF-TrkA

Fabry disease-associated globotriaosylceramide induces mechanical allodynia via activation of signaling through proNGF-p75 NTR but not mature NGF-TrkA

Fabry illness (FD) is an X-linked metabolic storage dysfunction arising from the deficiency of lysosomal α-galactosidase A, which ends up in the gradual accumulation of glycosphingolipids, primarily globotriaosylceramide (Gb3), all through the physique. Ache within the extremities is an early symptom of FD; nevertheless, the underlying pathophysiological mechanisms stay unknown. α-Galactosidase A knockout animals exhibit nociceptive behaviors, with enhanced expression ranges of a number of ion channels.

These traits are noticed in animals handled with nerve development issue (NGF). Right here, we aimed to elucidate the potential of NGF signaling as a reason behind FD-associated ache, utilizing intraplantar Gb3-treated mice displaying mechanical allodynia. Remedy with a neutralizing antibody towards a precursor of NGF (proNGF) or its receptor, p75 neurotrophin receptor (p75NTR), resulted within the restoration from Gb3-induced ache.

Conversely, anti-NGF and anti-tropomyosin receptor kinase A antibodies did not exert analgesic results. Gb3 injection had no results on the expression ranges of proNGF and p75NTR within the plantar pores and skin and dorsal root ganglia, suggesting that Gb3 prompts the ache pathway, presumably mediated via useful up-regulation of proNGF-p75NTR signaling.

Moreover, by pharmacological approaches utilizing a protein kinase A (PKA) inhibitor and a cholesterol-removing agent, we discovered that p75NTR-phosphorylating PKA and lipid rafts for phosphorylated p75NTR translocation have been required for Gb3-induced ache. These outcomes counsel that acute publicity to Gb3 induces mechanical allodynia through activation of the proNGF-p75NTR pathway, which includes lipid rafts and PKA. Our findings present new pathological insights into FD-associated ache, and counsel the necessity to develop therapeutic interventions concentrating on proNGF-p75NTR signaling.

Results of NGF Addition on Llama ( Lama glama) Sperm Traits After Cooling

To offer new insights into the mechanisms via which seminal plasma proteins can defend sperm from harm induced throughout refrigeration, we consider the likelihood that β-NGF can contribute to the advance of sperm high quality after cooling. First, β-NGF was detected in refrigerated sperm and in contrast with unrefrigerated sperm by western blotting of the proteins adsorbed by sperm, displaying that native β-NGF continues to be current even 24 h after cooling solely as an energetic kind.

Then, the impact of exogenous β-NGF on sperm high quality after cooling was evaluated. A complete of 12 ejaculates from male llamas (three ejaculates per male), have been obtained by electro-ejaculation, diluted 4:1 with buffer Hepes-balanced salt answer and centrifuged at 800 × g for eight min to take away the seminal plasma. Sperm have been suspended in Tris-citrate-fructose-egg yolk diluent for a last focus of 30 ×106/ml and cooled at 5°C for 24 h.

After refrigeration, the prolonged sperm have been equilibrated for five min at 37°C and divided into the next subgroups: sperm samples with out remedy (management) and sperm samples supplemented with exogenous human β-NGF (10, 100, and 500 ng/ml). At 5, 30, and 60 min of incubation sperm have been evaluated for sperm viability (utilizing eosin/nigrosin stain), sperm motility and vigor (noticed underneath gentle microscopy), and mitochondrial exercise (utilizing the JC-1 fluorescent marker).

Vigor information have been analyzed with the nonparametric Kruskal-Wallis take a look at. The remainder of the variables have been analyzed with a blended fashions method. Imply comparisons have been carried out utilizing Fisher’s LSD take a look at with a confidence stage of 95%. A principal parts evaluation was carried out to investigate the relationships between variables.

Remedy of 24 h cooled sperm with 10 or 100 ng/ml of human β-NGF elevated the share of whole motility and vigor (p < 0.05). Moreover, an incubation time of 60 min can be ample to enhance sperm high quality, since all variables are positively associated. The numerous enchancment noticed within the motility and vigor of post-refrigerated sperm means that supplementation with exogenous β-NGF could also be worthwhile for the advance of cooled llama sperm.

Fabry disease-associated globotriaosylceramide induces mechanical allodynia via activation of signaling through proNGF-p75 NTR but not mature NGF-TrkA

BmK NSPK, a Potent Potassium Channel Inhibitor from Scorpion Buthus martensii Karsch, Promotes Neurite Outgrowth through NGF/TrkA Signaling Pathway

Scorpion toxins signify a wide range of instruments to discover molecular mechanisms and mobile signaling pathways of many organic capabilities. These toxins are additionally promising lead compounds for growing therapies for a lot of neurological ailments. Within the present research, we purified a brand new scorpion toxin designated as BmK NSPK (Buthus martensii Karsch neurite-stimulating peptide concentrating on Okayv channels) from the BmK venom. The first construction was decided utilizing Edman degradation.

BmK NSPK straight inhibited outward Okay+ present with out affecting sodium channel actions, depolarized membrane, and elevated spontaneous calcium oscillation in spinal twine neurons (SCNs) at low nanomolar concentrations. BmK NSPK produced a nonmonotonic enhance on the neurite extension that peaked at ~10 nM. Mechanistic research demonstrated that BmK NSPK elevated the discharge of nerve development issue (NGF).

The tyrosine kinases A (TrkA) receptor inhibitor, GW 441756, eradicated the BmK NSPK-induced neurite outgrowth. BmK NSPK additionally elevated phosphorylation ranges of protein kinase B (Akt) that’s the downstream regulator of TrkA receptors.

Porcine Hepatocyte Growth Factor (HGF) ELISA Kit

DLR-HGF-p-48T 48T
EUR 656.4
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Hepatocyte Growth Factor (HGF) in samples from serum, plasma, tissue homogenates or other biological fluids.

Porcine Hepatocyte Growth Factor (HGF) ELISA Kit

DLR-HGF-p-96T 96T
EUR 858
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Hepatocyte Growth Factor (HGF) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Hepatocyte Growth Factor (HGF) ELISA Kit

DLR-HGF-Ra-48T 48T
EUR 544.8
Description: A sandwich quantitative ELISA assay kit for detection of Rat Hepatocyte Growth Factor (HGF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Hepatocyte Growth Factor (HGF) ELISA Kit

DLR-HGF-Ra-96T 96T
EUR 704.4
Description: A sandwich quantitative ELISA assay kit for detection of Rat Hepatocyte Growth Factor (HGF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Hepatocyte Growth Factor (HGF) ELISA Kit

DLR-HGF-Rb-48T 48T
EUR 544.8
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Hepatocyte Growth Factor (HGF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Hepatocyte Growth Factor (HGF) ELISA Kit

DLR-HGF-Rb-96T 96T
EUR 704.4
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Hepatocyte Growth Factor (HGF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-b-48Tests 48 Tests
EUR 619.2

Bovine Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-b-96Tests 96 Tests
EUR 859.2

Canine Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-c-48Tests 48 Tests
EUR 591.6

Canine Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-c-96Tests 96 Tests
EUR 819.6

Human Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-Hu-48Tests 48 Tests
EUR 390

Human Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-Hu-96Tests 96 Tests
EUR 530.4

Mouse Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-Mu-48Tests 48 Tests
EUR 536.4

Mouse Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-Mu-96Tests 96 Tests
EUR 741.6

Porcine Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-p-48Tests 48 Tests
EUR 696

Porcine Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-p-96Tests 96 Tests
EUR 968.4

Rat Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-Ra-48Tests 48 Tests
EUR 564

Rat Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-Ra-96Tests 96 Tests
EUR 781.2

Rabbit Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-Rb-48Tests 48 Tests
EUR 564

Rabbit Hepatocyte Growth Factor (HGF) ELISA Kit

RDR-HGF-Rb-96Tests 96 Tests
EUR 781.2

Bovine Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-b-48Tests 48 Tests
EUR 592.8

Bovine Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-b-96Tests 96 Tests
EUR 820.8

Canine Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-c-48Tests 48 Tests
EUR 566.4

Canine Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-c-96Tests 96 Tests
EUR 783.6

Human Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-Hu-48Tests 48 Tests
EUR 373.2

Human Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-Hu-96Tests 96 Tests
EUR 508.8

Mouse Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-Mu-48Tests 48 Tests
EUR 514.8

Mouse Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-Mu-96Tests 96 Tests
EUR 709.2

Porcine Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-p-48Tests 48 Tests
EUR 666

Porcine Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-p-96Tests 96 Tests
EUR 925.2

Rat Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-Ra-48Tests 48 Tests
EUR 540

Rat Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-Ra-96Tests 96 Tests
EUR 746.4

Rabbit Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-Rb-48Tests 48 Tests
EUR 540

Rabbit Hepatocyte Growth Factor (HGF) ELISA Kit

RD-HGF-Rb-96Tests 96 Tests
EUR 746.4

HGF antibody

70R-11547 100 ug
EUR 638.4
Description: Rabbit polyclonal HGF antibody

HGF antibody

10-2526 250 ug
EUR 590.4
Description: Mouse monoclonal HGF antibody

HGF antibody

70R-5700 50 ug
EUR 560.4
Description: Rabbit polyclonal HGF antibody

HGF antibody

70R-13854 100 ug
EUR 386.4
Description: Affinity purified Goat polyclonal HGF antibody

HGF Antibody

32218-100ul 100ul
EUR 302.4

HGF antibody

10R-H138A 500 ug
EUR 1652.4
Description: Mouse monoclonal HGF antibody

HGF Antibody

ABD6326 100 ug
EUR 525.6

HGF antibody

70R-HG004 100 ug
EUR 988.8
Description: Affinity purified Goat polyclonal HGF antibody

HGF antibody

70R-8599 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal HGF antibody

HGF antibody

70R-6637 50 ug
EUR 560.4
Description: Rabbit polyclonal HGF antibody

HGF Antibody

1-CSB-PA783451
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against HGF. Recognizes HGF from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000

HGF Antibody

DF6326 200ul
EUR 420

HGF Antibody

1-CSB-PA221214
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against HGF. Recognizes HGF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

HGF Antibody

1-CSB-PA254609
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against HGF. Recognizes HGF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

HGF Antibody

CSB-PA010327KA01HU-
EUR 402
Description: A polyclonal antibody against HGF. Recognizes HGF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:200-1:500, IHC:1:50-1:100

HGF Antibody

CSB-PA010327KA01HU-100ul 100ul
EUR 466.8
Description: A polyclonal antibody against HGF. Recognizes HGF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:200-1:500, IHC:1:50-1:100

HGF Antibody

R30164 100 ug
EUR 419

HGF Antibody

F40371-0.4ML 0.4 ml
EUR 379

HGF Antibody

F45472-0.4ML 0.4 ml
EUR 379

HGF

GT15204 100 ug
EUR 631.2

HGF antibody (biotin)

60R-HG003BT 100 ug
EUR 964.8
Description: Goat polyclonal HGF antibody (biotin) conjugated

Human HGF Antibody

32740-05111 150 ug
EUR 313.2

HGF activator Antibody

20-abx141127
  • EUR 427.20
  • EUR 644.40
  • EUR 260.40
  • 100 ul
  • 200 ul
  • 30 ul

HGF Polyclonal Antibody

ABP57387-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of HGF from Human. This HGF antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human HGF

HGF Polyclonal Antibody

ABP57387-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of HGF from Human. This HGF antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human HGF

HGF Polyclonal Antibody

ABP57387-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of HGF from Human. This HGF antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human HGF

HGF Conjugated Antibody

C32218 100ul
EUR 476.4

HGF Polyclonal Antibody

ES8380-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against HGF from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

HGF Polyclonal Antibody

ES8380-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against HGF from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Anti-HGF Antibody

PA1312 100ug/vial
EUR 400.8

Anti-HGF Antibody

PB9084 100ug/vial
EUR 400.8

Anti-HGF antibody

STJ97652 200 µl
EUR 236.4
Description: Rabbit polyclonal to HGF.

Anti-HGF antibody

STJ23940 100 µl
EUR 332.4
Description: This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.

Anti-HGF Antibody

RP1062 100ug/vial
EUR 352.8

HGF/ Rat HGF ELISA Kit

ELA-E0047r 96 Tests
EUR 1063.2

HGF protein

30R-2623 10 ug
EUR 408
Description: Purified recombinant Human HGF protein

HGF protein

30R-2624 10 ug
EUR 380.4
Description: Purified recombinant Human HGF protein

HGF protein

30R-AH020 10 ug
EUR 327.6
Description: Purified recombinant Human HGF protein

HGF protein

30R-AH025 5 ug
EUR 290.4
Description: Purified recombinant Human HGF protein

HGF siRNA

20-abx902455
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

HGF siRNA

20-abx919319
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

HGF siRNA

20-abx919320
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

HGF Human

PR15061 5 ug
EUR 577.2

HGF CHO

PR27049 2 ug
EUR 229.2

HGF Human

PR27050 2 ug
EUR 229.2

anti-HGF

YF-PA23875 50 ul
EUR 400.8
Description: Mouse polyclonal to HGF

anti-HGF

YF-PA12302 100 ug
EUR 483.6
Description: Rabbit polyclonal to HGF

Human HGF Antibody (Biotin Conjugate)

32740-05121 150 ug
EUR 442.8

Hepatocyte Growth Factor (HGF) Antibody

20-abx141201
  • EUR 427.20
  • EUR 644.40
  • EUR 260.40
  • 100 ul
  • 200 ul
  • 30 ul

Hepatocyte Growth Factor (HGF) Antibody

20-abx102372
  • EUR 376.80
  • EUR 159.60
  • EUR 1011.60
  • EUR 526.80
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx102373
  • EUR 376.80
  • EUR 159.60
  • EUR 1011.60
  • EUR 526.80
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx102374
  • EUR 376.80
  • EUR 159.60
  • EUR 1011.60
  • EUR 526.80
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx102375
  • EUR 427.20
  • EUR 1128.00
  • EUR 577.20
  • EUR 184.80
  • EUR 326.40
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx102376
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx102377
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx104891
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx001106
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Hepatocyte Growth Factor (HGF) Antibody

abx117058-100ug 100 ug
EUR 560.4

Hepatocyte Growth Factor (HGF) Antibody

abx029391-400ul 400 ul
EUR 627.6

Hepatocyte Growth Factor (HGF) Antibody

abx029391-80l 80 µl
EUR 343.2

Hepatocyte Growth Factor (HGF) Antibody

abx025436-100ul 100 ul
EUR 627.6

Hepatocyte Growth Factor (HGF) Antibody

abx025437-400ul 400 ul
EUR 627.6

Hepatocyte Growth Factor (HGF) Antibody

abx025437-80l 80 µl
EUR 343.2

Hepatocyte Growth Factor (HGF) Antibody

20-abx241534
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Hepatocyte Growth Factor (HGF) Antibody

20-abx241535
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Hepatocyte Growth Factor (HGF) Antibody

20-abx323389
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx172782
  • EUR 1011.60
  • EUR 526.80
  • 1 mg
  • 200 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx172783
  • EUR 1011.60
  • EUR 526.80
  • 1 mg
  • 200 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx172784
  • EUR 1045.20
  • EUR 543.60
  • 1 mg
  • 200 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx172785
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx176817
  • EUR 1362.00
  • EUR 661.20
  • 1 mg
  • 200 ug

Hepatocyte Growth Factor (HGF) Antibody

20-abx176819
  • EUR 1545.60
  • EUR 744.00
  • 1 mg
  • 200 ug

Monoclonal HGF Antibody, Clone: 489CT6.12.6

AMM02413G 0.1ml
EUR 580.8
Description: A Monoclonal antibody against Human HGF. The antibodies are raised in Mouse and are from clone 489CT6.12.6. This antibody is applicable in WB, E

Hepatocyte Growth Factor Antibody (HGF)

F40371-0.08ML 0.08 ml
EUR 165

Hepatocyte Growth Factor Antibody (HGF)

F45472-0.08ML 0.08 ml
EUR 165

Hepatocyte Growth Factor Antibody (HGF)

V7839-100UG 100 ug
EUR 499
Description: This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.

Hepatocyte Growth Factor Antibody (HGF)

V7839-20UG 20 ug
EUR 219
Description: This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.

Hepatocyte Growth Factor Antibody (HGF)

V7839SAF-100UG 100 ug
EUR 499
Description: This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.

HGF Rabbit pAb

A1193-100ul 100 ul
EUR 369.6

HGF Rabbit pAb

A1193-200ul 200 ul
EUR 550.8

HGF Rabbit pAb

A1193-20ul 20 ul
EUR 219.6

HGF Rabbit pAb

A1193-50ul 50 ul
EUR 267.6

HGF Recombinant Protein

40-184-0002mg 0.002 mg
EUR 311.1
Description: HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear 697 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 234 amino acid residues.

HGF Recombinant Protein

40-184-001mg 0.01 mg
EUR 437.1
Description: HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear 697 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 234 amino acid residues.

HGF, human recombinant

4509-10
EUR 333.6

HGF, human recombinant

4509-1000
EUR 10336.8

HGF, human recombinant

4510-10
EUR 333.6

HGF, human recombinant

4510-1000
EUR 10336.8

HGF, human recombinant

4510-50
EUR 1149.6

HGF Blocking Peptide

33R-3251 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HGF antibody, catalog no. 70R-5700

HGF Recombinant Protein

40-580-0005mg 0.005 mg
EUR 311.1
Description: HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Murine HGF is expressed as a linear 728 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 233 amino acid residues.*Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

HGF Recombinant Protein

40-580-002mg 0.02 mg
EUR 437.1
Description: HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Murine HGF is expressed as a linear 728 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 233 amino acid residues.*Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

HGF Recombinant Protein

40-627 5 ug
EUR 311.1
Description: HGF is a potent, mesenchymally-derived mitogen for mature parenchymal hepatocytes, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include the induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear, polypeptide-precursor glycoprotein containing 697 amino acid residues. Proteolytic processing of this precursor generates the biologically active heterodimeric form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held together by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 234 amino acid residues. Recombinant Human HGF, sourced from HEK293 cells, is a 79.4 kDa polypeptide consisting of 695 amino acid residues. As a result of glycosylation, Recombinant Human HGF migrates with an apparent molecular mass of approximately 68-85 kDa by SDS-PAGE gel, under non-reducing conditions.

HGF Blocking Peptide

33R-9625 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HGF antibody, catalog no. 70R-6637

HGF Recombinant Protein

11-302 0.1 mg
EUR 821.4
Description: Hepatocyte growth factor (HGF) is a paracrine cellular growth, motility and morphogenic factor. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. In addition, HGF has been implicated in a variety of cancers, including of the lungs, pancreas, thyroid, colon, and breast.

HGF Blocking Peptide

20-abx061899
  • EUR 309.60
  • EUR 460.80
  • 1 mg
  • 5 mg

HGF, murine recombinant

7160-10
EUR 288

HGF, murine recombinant

7160-50
EUR 1032

HGF Blocking Peptide

DF6326-BP 1mg
EUR 234

HGF cloning plasmid

CSB-CL010327HU1-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the HGF gene.

HGF cloning plasmid

CSB-CL010327HU2-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the HGF gene.

HGF cloning plasmid

CSB-CL010327HU3-10ug 10ug
EUR 865.2
Description: A cloning plasmid for the HGF gene.

Human HGF AssayLite Antibody (FITC Conjugate)

32740-05141 150 ug
EUR 513.6

Human HGF AssayLite Antibody (RPE Conjugate)

32740-05151 150 ug
EUR 513.6

Human HGF AssayLite Antibody (APC Conjugate)

32740-05161 150 ug
EUR 513.6

Human HGF AssayLite Antibody (PerCP Conjugate)

32740-05171 150 ug
EUR 565.2

Hepatocyte Growth Factor (HGF) Antibody Pair

20-abx370089
  • EUR 1429.20
  • EUR 944.40
  • 10 × 96 tests
  • 5 × 96 tests

Hepatocyte Growth Factor (HGF) Antibody (FITC)

20-abx273861
  • EUR 410.40
  • EUR 260.40
  • EUR 1178.40
  • EUR 594.00
  • EUR 343.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody (FITC)

20-abx274174
  • EUR 560.40
  • EUR 292.80
  • EUR 1663.20
  • EUR 777.60
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody (APC)

20-abx274635
  • EUR 510.00
  • EUR 276.00
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody (Biotin)

20-abx273129
  • EUR 543.60
  • EUR 292.80
  • EUR 1545.60
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody (Biotin)

20-abx271900
  • EUR 393.60
  • EUR 260.40
  • EUR 1095.60
  • EUR 560.40
  • EUR 343.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatocyte Growth Factor (HGF) Antibody (APC)

20-abx176818
  • EUR 1412.40
  • EUR 693.60
  • 1 mg
  • 200 ug

Human HGF ELISA kit

55R-1586 1 kit
EUR 603.6
Description: ELISA kit for the detection of Human HGF in the research laboratory

Mouse HGF ELISA kit

55R-2088 96 tests
EUR 854.4
Description: ELISA Kit for detection of Hepatocyte Growth Factor in the research laboratory

Human HGF ELISA kit

55R-2128 96 tests
EUR 919.2
Description: ELISA Kit for detection of HGF in the research laboratory

HGF activator Blocking Peptide

20-abx061825
  • EUR 309.60
  • EUR 460.80
  • 1 mg
  • 5 mg

HGF protein (His tag)

80R-3851 100 ug
EUR 392.4
Description: Purified recombinant HGF protein (His tag)

Human HGF shRNA Plasmid

20-abx952100
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Rat HGF shRNA Plasmid

20-abx984496
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse HGF shRNA Plasmid

20-abx970796
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Porcine HGF ELISA Kit

EPH0215 96Tests
EUR 625.2

Rabbit HGF ELISA Kit

ERTH0215 96Tests
EUR 625.2

Rat HGF ELISA Kit

ERH0215 96Tests
EUR 625.2

Mouse HGF ELISA Kit

EMH0215 96Tests
EUR 625.2

Monkey HGF ELISA Kit

EMKH0215 96Tests
EUR 625.2

Human HGF ELISA Kit

EHH0215 96Tests
EUR 625.2

Goat HGF ELISA Kit

EGTH0215 96Tests
EUR 625.2

Bovine HGF ELISA Kit

EBH0215 96Tests
EUR 625.2

Canine HGF ELISA Kit

ECH0215 96Tests
EUR 625.2

Chicken HGF ELISA Kit

ECKH0215 96Tests
EUR 625.2

Anserini HGF ELISA Kit

EAH0215 96Tests
EUR 625.2

HGF ELISA KIT|Human

EF000130 96 Tests
EUR 826.8

Human HGF ELISA kit

LF-EK50065 1×96T
EUR 777.6

Sheep HGF ELISA Kit

ESH0215 96Tests
EUR 625.2

HGF (CHO-expressed), Human

HY-P7121 10ug
EUR 267.6

Human HGF ELISA Kit

ELA-E0047h 96 Tests
EUR 988.8

HGF (human) ELISA Kit

K4781-100 100 assays
EUR 1000.8
Description: Sensitive, Colorimetric Assay

Recombinant Human HGF Protein

PROTP14210-6 10ug
EUR 380.4
Description: HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear 697 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 234 amino acid residues.*Manufactured using (BTI-Tn-5B1-4) cells under license from Boyce Thompson Institute for Plant Research, Inc.

Recombinant Murine HGF Protein

PROTQ08048 20ug
EUR 380.4
Description: HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Murine HGF is expressed as a linear 728 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 233 amino acid residues. *Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

Rat HGF ELISA Kit

STJ150064 1 kit
EUR 494.4
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of HGF in Rat serum, plasma and other biological fluids

Human HGF ELISA Kit

STJ150246 1 kit
EUR 494.4
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of HGF in human serum, plasma and other biological fluids

Human HGF ELISA Kit

RK00091 96 Tests
EUR 625.2

Mouse HGF ELISA Kit

RK00371 96 Tests
EUR 625.2

Anti-HGF/SF Monoclonal Antibody (7-2)

M00089 100ug
EUR 518.4
Description: Mouse Monoclonal HGF/SF Antibody (7-2). Validated in IHC, WB and tested in Human, Mouse.

Hepatocyte Growth Factor (HGF) Monoclonal Antibody (Human)

4-MAA047Hu22
  • EUR 265.20
  • EUR 2536.80
  • EUR 642.00
  • EUR 328.80
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Hepatocyte Growth Factor (HGF)

Genorise® Anti-canine HGF Polyclonal Antibody

GR105170 100 ug
EUR 525.6

Genorise® Anti-Equine HGF Polyclonal Antibody

GR105191 100 ug
EUR 525.6

Genorise® Biotinylated Bovine HGF polyclonal antibody

GR134002 50 µg
EUR 477.6

Hepatocyte Growth Factor (HGF) Polyclonal Antibody (Dog)

4-PAA047Ca01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Hepatocyte Growth Factor (HGF)

Hepatocyte Growth Factor (HGF) Polyclonal Antibody (Human)

4-PAA047Hu01
  • EUR 235.20
  • EUR 2044.80
  • EUR 530.40
  • EUR 283.20
  • EUR 229.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Hepatocyte Growth Factor (HGF)

Hepatocyte Growth Factor (HGF) Polyclonal Antibody (Human)

4-PAA047Hu02
  • EUR 235.20
  • EUR 2044.80
  • EUR 530.40
  • EUR 283.20
  • EUR 229.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Hepatocyte Growth Factor (HGF)

Hepatocyte Growth Factor (HGF) Polyclonal Antibody (Human)

4-PAA047Hu03
  • EUR 235.20
  • EUR 2044.80
  • EUR 530.40
  • EUR 283.20
  • EUR 229.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Hepatocyte Growth Factor (HGF)

Hepatocyte Growth Factor (HGF) Polyclonal Antibody (Mouse)

4-PAA047Mu01
  • EUR 283.20
  • EUR 2805.60
  • EUR 703.20
  • EUR 352.80
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Hepatocyte Growth Factor (HGF)

Hepatocyte Growth Factor (HGF) Polyclonal Antibody (Rat)

4-PAA047Ra01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Hepatocyte Growth Factor (HGF)

Human CellExp? HGF, Human Recombinant

6456-10
EUR 464.4

Human CellExp? HGF, Human Recombinant

6456-50
EUR 1677.6

Rat Hepatocyte growth factor (Hgf)

1-CSB-RP084844R
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Rat Hepatocyte growth factor(Hgf),partial expressed in E.coli

HGF ELISA Kit (Human) (OKBB00157)

OKBB00157 96 Tests
EUR 606
Description: Description of target: Hepatocyte growth factor (HGF) is the most potent mitogen for mature parenchymal hepatocytes in primary culture, and seems to be a hepatotrophic factor that acts as a trigger for liver regeneration after partial hepatectomy and liver injury. HGF has a relative molecular mass (Mr) of 82,000 and is a heterodimer composed of a large alpha-subunit of Mr 69,000 and a small beta-subunit of Mr 34,000.1 The protein consists of 728 amino acid residues, including a possible signal peptide at the N-terminus.2 HGF may serve as a paracrine mediator to control placental development and growth.3 This growth factor may play an important role as a paracrine mediator of the proliferation of melanocytes and endothelial cells, as well as cells of epithelial origin.4 The gene encoding the human HGF is assigned to human chromosome 7.5;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 5 pg/ml

HGF ELISA Kit (Rat) (OKBB00592)

OKBB00592 96 Wells
EUR 606
Description: Description of target: Hepatocyte growth factor (HGF) is the most potent mitogen for mature parenchymal hepatocytes in primary culture, and seems to be a hepatotrophic factor that acts as a trigger for liver regeneration after partial hepatectomy and liver injury. HGF has a relative molecular mass (Mr) of 82,000 and is a heterodimer composed of a large alpha-subunit of Mr 69,000 and a small beta-subunit of Mr 34,000.1 The protein consists of 728 amino acid residues, including a possible signal peptide at the N-terminus.2 HGF may serve as a paracrine mediator to control placental development and growth.3 This growth factor may play an important role as a paracrine mediator of the proliferation of melanocytes and endothelial cells, as well as cells of epithelial origin.4 The gene encoding the human HGF is assigned to human chromosome 7.;Species reactivity: Rat;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

HGF ELISA Kit (Mouse) (OKBB00918)

OKBB00918 96 Wells
EUR 606
Description: Description of target: Hepatocyte growth factor(HGF) is the most potent mitogen for mature parenchymal hepatocytes in primary culture, and seems to be a hepatotrophic factor that acts as a trigger for liver regeneration after partial hepatectomy and liver injury. HGF has a relative molecular mass(Mr) of 82,000 and is a heterodimer composed of a large alpha-subunit of Mr 69,000 and a small beta-subunit of Mr 34,000. The protein consists of 728 amino acid residues, including a possible signal peptide at the N-terminus. HGF may serve as a paracrine mediator to control placental development and growth. This growth factor may play an important role as a paracrine mediator of the proliferation of melanocytes and endothelial cells, as well as cells of epithelial origin. The gene encoding the human HGF is assigned to human chromosome 7.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

Human HGF PicoKine ELISA Kit

EK0369 96 wells
EUR 510
Description: For quantitative detection of human HGF in cell culture supernates, serum and plasma(EDTA, citrate).

Mouse HGF PicoKine ELISA Kit

EK1217 96 wells
EUR 510
Description: For quantitative detection of mouse HGF in cell culture supernates, serum and plasma(EDTA, citrate).

Rat HGF PicoKine ELISA Kit

EK1301 96 wells
EUR 510
Description: For quantitative detection of rat HGF in cell culture supernates, serum and plasma(EDTA, citrate).

HGF ELISA Kit (Bovine) (OKEH07247)

OKEH07247 96 Wells
EUR 1154.4
Description: Description of target: ;Species reactivity: Bovine;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078ng/mL

HGF ELISA Kit (Rat) (OKAN04591)

OKAN04591 96 Wells
EUR 950.4
Description: Description of target: plays a role in positive regulation of cell proliferation; may promote entry into the cell cycle [RGD, Feb 2006];Species reactivity: Rat;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 5.9 pg/mL

HGF ELISA Kit (Canine) (OKAN05688)

OKAN05688 96 Wells
EUR 950.4
Description: Description of target: ;Species reactivity: Canine;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 5.6 pg/mL

These information show that BmK NSPK is a brand new voltage-gated potassium (Okayv) channel inhibitor that augments neurite extension through NGF/TrkA signaling pathway. Okayv channels could signify molecular targets to modulate SCN improvement and regeneration and to develop the therapies for spinal twine damage.

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