EXPRESS: Differentiation of the 50B11 dorsal root cells into NGF and GDNF responsive nociceptor subtypes
The embryonic rat dorsal root ganglion (DRG) neuron-derived 50B11 cell line is a promising sensory neuron mannequin expressing markers attribute of NGF and GDNF-dependent C-fibre nociceptors. Whether or not these cells have the capability to turn into distinct nociceptive subtypes primarily based on NGF- or GDNF-dependence has not been investigated. Right here we present that
Read More