Nanofibrous bicomponent scaffolds for the dual delivery of NGF and GDNF: controlled release of growth factors and their biological effects
Electrospun fibrous scaffolds able to offering twin progress issue supply in a managed method have distinctive benefits for tissue engineering. On this examine, we’ve got investigated the formation, construction, and traits/properties of fibrous bicomponent scaffolds for the twin supply of glial cell line-derived neurotrophic issue (GDNF) and nerve progress issue (NGF) for peripheral nerve tissue regeneration.
GDNF and NGF have been integrated into core-shell structured poly(lactic-co-glycolic acid) (PLGA) and poly (D,L-lactic acid) (PDLLA) nanofibers, respectively, by way of emulsion electrospinning. Utilizing dual-source dual-power electrospinning, bicomponent scaffolds composed of GDNF/PLGA fibers and NGF/PDLLA fibers with totally different fiber part ratios have been produced.
The construction, properties, and in vitro launch habits of mono- and bicomponent scaffolds have been systematically investigated. Concurrent and sustained launch of GDNF and NGF from bicomponent scaffolds was achieved and their launch profiles could possibly be tuned. In vitro organic investigations have been carried out. Rat pheochromocytoma cells have been discovered to connect, unfold, and proliferate on all scaffolds.
The discharge of progress components from scaffolds may induce a lot improved neurite outgrowth and neural differentiation. GDNF and NGF launched from GDNF/PLGA scaffolds and NGF/PDLLA scaffolds, respectively, may induce dose-dependent neural differentiation individually. GDNF and NGF launched from bicomponent scaffolds exerted a synergistic impact on selling neural differentiation.
Redox proteomics reveals an interdependence of redox modification and placement of adhesome proteins in NGF-treated PC12 cells
Proteomics research have revealed that adhesomes are assembled from a plethora of proteins at integrin-mediated mobile contact websites with the extracellular matrix. By combining dimedone-trapping of sulfenylated proteins with the purification of the adhesome complicated, we prolonged earlier proteomics approaches on adhesomes to a redox proteomic evaluation. This added a brand new side of adhesome complexity as particular person adhesome proteins change their redox state in response to environmental alerts.
As mannequin system, rat pheochromocytoma PC12 cells have been studied in touch with sort IV collagen and in response to nerve progress issue (NGF). NGF stimulates the endogenous manufacturing of reactive oxygen species (ROS) and the formation of neurite-like cell protrusions, that are anchored to the substratum by way of adhesomes.
Dimedone detects the reversible oxidation of cysteine thiol teams into sulfenic acid teams which was utilized in proteomic evaluation of adhesome proteins revealing that sulfenation and placement of proteins mutually affect one another. For some proteins, recognized by the redox proteomics method, amongst them Nck-associated protein-1 (Nap-1), proximity ligation evaluation and co-immunoprecipitation assays proved that protein sulfenylation websites colocalize with adhesomes of protrusions.
In conclusion, the suprastructural composition and performance of adhesomes is redox-regulated by ROS. Of curiosity on this respect, isoform-selective pharmacological inhibition of NADPH-oxidases (Noxs) decreased the adhesomal location of the collagen-binding α1β1 integrin and the size of the outgrowing neurites, indicative of a task of Nox isoforms within the redox-regulation of adhesomes. Thus, our novel redox proteomics method not solely revealed redox-modifications and the potential redox-regulation of adhesomes and their constituents however it could additionally present a device to research the ROS-stimulated neurite restore of peripheral neurons.
NGF– and BDNF-dependent DRG sensory neurons deploy distinct degenerative signaling mechanisms
The nerve progress issue (NGF) and brain-derived neurotrophic issue (BDNF) are trophic components required by distinct inhabitants of sensory neurons throughout improvement of the nervous system. Neurons that fail to obtain acceptable trophic help are misplaced throughout this era of naturally occurring cell loss of life. Within the final decade, our understanding of the signalling pathways regulating neuronal loss of life following NGF deprivation has superior considerably. Nevertheless, the signaling mechanisms selling BDNF-deprivation induced sensory neuron degeneration are largely unknown.
Utilizing a well-established in vitro tradition mannequin of dorsal root ganglion (DRG), we’ve got examined degeneration mechanisms triggered upon BDNF withdrawal in sensory neurons. Our outcomes point out variations and similarities between the molecular signalling pathways behind NGF and BDNF deprivation-induced loss of life. For example, we noticed that the inhibition of Trk receptors (Okay252a), PKC (Gö6976), protein translation (cycloheximide) or caspases (zVAD-fmk) gives safety from NGF deprivation-induced loss of life however not from degeneration evoked by BDNF-withdrawal.
Curiously, degeneration of BDNF-dependent sensory neurons requires BAX and seems to depend on reactive oxygen species era slightly than caspases to induce degeneration. These outcomes spotlight the complexity and divergence of mechanisms regulating developmental sensory neuron loss of life.
Important assertion The elimination of neuronal cells generated in extra throughout embryonic phases characterizes the maturation of the nervous system. Right here we deal with the developmental cell loss of life mechanisms of BDNF-dependent dorsal root ganglion neurons in vitro, evaluating and distinction them with these deployed in NGF-dependent sensory neurons.
We observe a number of necessary variations between the molecular signalling pathways behind NGF and BDNF deprivation-induced loss of life. Considerably, degeneration of BDNF-dependent sensory neurons requires BAX however not caspase activation, as an alternative reactive oxygen species era seems to play a key position in degeneration. This work highlights the complexity of cell loss of life mechanisms in distinct embryonic sensory neuron populations.
Native injections of β-NGF accelerates endochondral fracture restore by selling cartilage to bone conversion
There are at present no pharmacological approaches in fracture therapeutic designed to therapeutically stimulate endochondral ossification. On this examine, we take a look at nerve progress issue (NGF) as an understudied therapeutic for fracture restore. We first characterised endogenous expression of Ngf and its receptor tropomyosin receptor kinase A (TrkA) throughout tibial fracture restore, discovering that they peak in the course of the cartilaginous section.
We then examined two injection regimens and located that native β-NGF injections in the course of the endochondral/cartilaginous section promoted osteogenic marker expression. Gene expression knowledge from β-NGF stimulated cartilage callus explants present a promotion in markers related to endochondral ossification resembling Ihh, Alpl, and Sdf-1. Gene ontology enrichment evaluation revealed the promotion of genes related to Wnt activation, PDGF- and integrin-binding.
Subsequent histological evaluation confirmed Wnt activation following native β-NGF injections. Lastly, we reveal useful enhancements to bone therapeutic following native β-NGF injections which resulted in a lower in cartilage and improve of bone quantity. Furthermore, the newly fashioned bone contained larger trabecular quantity, connective density, and bone mineral density.
 NGFRAP1 Antibody |
|
E94635 |
EnoGene |
100μg |
EUR 255 |
|
Description: Available in various conjugation types. |
NGFRAP1 Antibody |
|
MBS7126007-005mL |
MyBiosource |
0.05mL |
EUR 190 |
NGFRAP1 Antibody |
|
MBS7126007-01mL |
MyBiosource |
0.1mL |
EUR 270 |
NGFRAP1 Antibody |
|
MBS7126007-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1205 |
NGFRAP1 Antibody |
|
MBS9403353-01mL |
MyBiosource |
0.1mL |
EUR 305 |
NGFRAP1 Antibody |
|
MBS9403353-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1230 |
NGFRAP1 Antibody |
|
MBS8500233-01mg |
MyBiosource |
0.1mg |
EUR 325 |
NGFRAP1 Antibody |
|
MBS8500233-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
NGFRAP1 Antibody |
|
MBS8500233-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
NGFRAP1 Antibody |
|
MBS8500233-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
NGFRAP1 Antibody |
|
MBS8500233-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
 anti- NGFRAP1 antibody |
|
FNab05721 |
FN Test |
100µg |
EUR 658.5 |
|
|
|
Description: Antibody raised against NGFRAP1 |
) NGFRAP1 Antibody (N-term) |
|
MBS9209327-008mL |
MyBiosource |
0.08mL |
EUR 210 |
NGFRAP1 Antibody (N-term) |
|
MBS9209327-04mL |
MyBiosource |
0.4mL |
EUR 430 |
NGFRAP1 Antibody (N-term) |
|
MBS9209327-5x04mL |
MyBiosource |
5x0.4mL |
EUR 1910 |
 NGFRAP1 polyclonal antibody |
|
BS8819 |
Bioworld Biotech |
50ul |
EUR 358 |
|
|
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Description: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
 NGFRAP1 Conjugated Antibody |
|
C36629 |
SAB |
100ul |
EUR 476.4 |
 NGFRAP1 Polyclonal Antibody |
|
MBS2536096-006mL |
MyBiosource |
0.06mL |
EUR 190 |
NGFRAP1 Polyclonal Antibody |
|
MBS2536096-012mL |
MyBiosource |
0.12mL |
EUR 265 |
NGFRAP1 Polyclonal Antibody |
|
MBS2536096-02mL |
MyBiosource |
0.2mL |
EUR 415 |
NGFRAP1 Polyclonal Antibody |
|
MBS2536096-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1835 |
NGFRAP1 Polyclonal Antibody |
|
MBS9238280-01mL |
MyBiosource |
0.1mL |
EUR 415 |
NGFRAP1 Polyclonal Antibody |
|
MBS9238280-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1841 |
NGFRAP1 Polyclonal Antibody |
|
MBS9125077-002mL |
MyBiosource |
0.02mL |
EUR 200 |
NGFRAP1 Polyclonal Antibody |
|
MBS9125077-005mL |
MyBiosource |
0.05mL |
EUR 255 |
NGFRAP1 Polyclonal Antibody |
|
MBS9125077-01mL |
MyBiosource |
0.1mL |
EUR 345 |
NGFRAP1 Polyclonal Antibody |
|
MBS9125077-02mL |
MyBiosource |
0.2mL |
EUR 545 |
NGFRAP1 Polyclonal Antibody |
|
MBS9125077-5x02mL |
MyBiosource |
5x0.2mL |
EUR 2265 |
NGFRAP1 Conjugated Antibody |
|
MBS9447088-01mLAF350 |
MyBiosource |
0.1mL(AF350) |
EUR 480 |
NGFRAP1 Conjugated Antibody |
|
MBS9447088-01mLAF405 |
MyBiosource |
0.1mL(AF405) |
EUR 480 |
NGFRAP1 Conjugated Antibody |
|
MBS9447088-01mLAF488 |
MyBiosource |
0.1mL(AF488) |
EUR 480 |
NGFRAP1 Conjugated Antibody |
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MBS9447088-01mLAF555 |
MyBiosource |
0.1mL(AF555) |
EUR 480 |
NGFRAP1 Conjugated Antibody |
|
MBS9447088-01mLBiotin |
MyBiosource |
0.1mL(Biotin) |
EUR 480 |
NGFRAP1 Polyclonal Antibody |
|
RD84401A-120uL |
Reddot Biotech |
120μL |
EUR 360 |
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|
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Description: Protein BEX3is aproteinthat in humans is encoded by theNGFRAP1gene. May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death By similarity. May play an important role in the pathogenesis of neurogenetic diseases. |
NGFRAP1 Polyclonal Antibody |
|
RD84401A-200uL |
Reddot Biotech |
200μL |
EUR 630 |
|
|
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Description: Protein BEX3is aproteinthat in humans is encoded by theNGFRAP1gene. May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death By similarity. May play an important role in the pathogenesis of neurogenetic diseases. |
NGFRAP1 Polyclonal Antibody |
|
RD84401A-60uL |
Reddot Biotech |
60μL |
EUR 204 |
|
|
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Description: Protein BEX3is aproteinthat in humans is encoded by theNGFRAP1gene. May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death By similarity. May play an important role in the pathogenesis of neurogenetic diseases. |
) Polyclonal NGFRAP1 Antibody (C-Term) |
|
APG00487G |
Leading Biology |
0.1mg |
EUR 580.8 |
|
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human NGFRAP1 (C-Term). This antibody is tested and proven to work in the following applications: |
 NGFRAP1 Rabbit Polyclonal Antibody |
|
55169 |
SAB |
100ul |
EUR 439 |
NGFRAP1 Rabbit Polyclonal Antibody |
|
MBS9466202-005mL |
MyBiosource |
0.05mL |
EUR 300 |
NGFRAP1 Rabbit Polyclonal Antibody |
|
MBS9466202-01mL |
MyBiosource |
0.1mL |
EUR 390 |
NGFRAP1 Rabbit Polyclonal Antibody |
|
MBS9466202-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1610 |
 Polyclonal NGFRAP1 / NADE / Bex Antibody |
|
APR02251G |
Leading Biology |
0.05mg |
EUR 580.8 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NGFRAP1 / NADE / Bex . This antibody is tested and proven to work in the following applications: |
 Blocking Peptide) NGFRAP1 Antibody (N-term) Blocking Peptide |
|
MBS9223075-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
 NGFRAP1 |
|
MBS8563159-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
NGFRAP1 |
|
MBS8563159-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
NGFRAP1 |
|
MBS8563159-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
NGFRAP1 |
|
MBS8563159-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
NGFRAP1 |
|
MBS8536311-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
NGFRAP1 |
|
MBS8536311-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
NGFRAP1 |
|
MBS8536311-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
NGFRAP1 |
|
MBS8536311-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
 NGFRAP1 Polyclonal Antibody Bio Conjugated |
|
MBS9463986-01mL |
MyBiosource |
0.1mL |
EUR 595 |
NGFRAP1 Polyclonal Antibody Bio Conjugated |
|
MBS9463986-5x01mL |
MyBiosource |
5x0.1mL |
EUR 2525 |
 (M01), Clone: 4E6) Monoclonal NGFRAP1 Antibody (monoclonal) (M01), Clone: 4E6 |
|
AMM03857G |
Leading Biology |
0.1mg |
EUR 580.8 |
|
Description: A Monoclonal antibody against Human NGFRAP1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4E6. This antibody is applicable in WB, E |
 OAAB13501-400UL - NGFRAP1 Antibody - N-terminal region |
|
OAAB13501-400UL |
Aviva Systems Biology |
400ul |
EUR 389 |
|
|
 NGFRAP1 Peptide |
|
46-876P |
ProSci |
0.1 mg |
EUR 405.6 |
|
Description: NGFRAP1 Peptide |
 Rat NGFRAP1 siRNA |
|
20-abx925863 |
Abbexa |
-
Ask for price
-
Ask for price
|
|
|
|
) NGFRAP1 siRNA (Rat) |
|
MBS8205193-15nmol |
MyBiosource |
15nmol |
EUR 405 |
NGFRAP1 siRNA (Rat) |
|
MBS8205193-30nmol |
MyBiosource |
30nmol |
EUR 565 |
NGFRAP1 siRNA (Rat) |
|
MBS8205193-5x30nmol |
MyBiosource |
5x30nmol |
EUR 2450 |
 NGFRAP1 Rabbit pAb |
|
A7296 |
Abclonal |
200μL |
EUR 173.58 |
NGFRAP1 Rabbit pAb |
|
A7296-100ul |
Abclonal |
100 ul |
EUR 369.6 |
NGFRAP1 Rabbit pAb |
|
A7296-200ul |
Abclonal |
200 ul |
EUR 550.8 |
NGFRAP1 Rabbit pAb |
|
A7296-20ul |
Abclonal |
20 ul |
EUR 219.6 |
NGFRAP1 Rabbit pAb |
|
A7296-50ul |
Abclonal |
50 ul |
EUR 267.6 |
NGFRAP1 Rabbit pAb |
|
E2507296 |
EnoGene |
100ul |
EUR 225 |
|
Description: Available in various conjugation types. |
NGFRAP1 Rabbit pAb |
|
E45R27268N |
EnoGene |
50 ul |
EUR 297.75 |
NGFRAP1 Rabbit pAb |
|
MBS8546713-01mL |
MyBiosource |
0.1mL |
EUR 305 |
NGFRAP1 Rabbit pAb |
|
MBS8546713-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
NGFRAP1 Rabbit pAb |
|
MBS8546713-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
NGFRAP1 Rabbit pAb |
|
MBS8546713-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
NGFRAP1 Rabbit pAb |
|
MBS8546713-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
 Mouse NGFRAP1 siRNA |
|
20-abx925864 |
Abbexa |
-
Ask for price
-
Ask for price
|
|
|
|
 Human NGFRAP1 siRNA |
|
20-abx903554 |
Abbexa |
-
Ask for price
-
Ask for price
|
|
|
|
) NGFRAP1 siRNA (Mouse) |
|
MBS828327-15nmol |
MyBiosource |
15nmol |
EUR 405 |
NGFRAP1 siRNA (Mouse) |
|
MBS828327-30nmol |
MyBiosource |
30nmol |
EUR 565 |
NGFRAP1 siRNA (Mouse) |
|
MBS828327-5x30nmol |
MyBiosource |
5x30nmol |
EUR 2450 |
) NGFRAP1 siRNA (Human) |
|
MBS8231564-15nmol |
MyBiosource |
15nmol |
EUR 405 |
NGFRAP1 siRNA (Human) |
|
MBS8231564-30nmol |
MyBiosource |
30nmol |
EUR 565 |
NGFRAP1 siRNA (Human) |
|
MBS8231564-5x30nmol |
MyBiosource |
5x30nmol |
EUR 2450 |
 Antibody) Nerve Growth Factor Receptor-Associated Protein 1 (NGFRAP1) Antibody |
|
abx029967-400l |
Abbexa |
400 µl |
EUR 518.75 |
Nerve Growth Factor Receptor-Associated Protein 1 (NGFRAP1) Antibody |
|
abx029967-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
|
Nerve Growth Factor Receptor-Associated Protein 1 (NGFRAP1) Antibody |
|
abx029967-80l |
Abbexa |
80 µl |
EUR 250 |
|
|
Nerve Growth Factor Receptor-Associated Protein 1 (NGFRAP1) Antibody |
|
abx005503-100l |
Abbexa |
100 µl |
EUR 175 |
Nerve Growth Factor Receptor-Associated Protein 1 (NGFRAP1) Antibody |
|
20-abx005503 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
|
- 20 ul
- 50 ul
- 100 ul
- 200 ul
|
|
|
Nerve Growth Factor Receptor-Associated Protein 1 (NGFRAP1) Antibody |
|
abx433035-100g |
Abbexa |
100 µg |
EUR 250 |
Nerve Growth Factor Receptor-Associated Protein 1 (NGFRAP1) Antibody |
|
abx433035-200ul |
Abbexa |
200 ul |
EUR 343.2 |
|
|
Nerve Growth Factor Receptor-Associated Protein 1 (NGFRAP1) Antibody |
|
abx235721-100g |
Abbexa |
100 µg |
EUR 350 |
Nerve Growth Factor Receptor-Associated Protein 1 (NGFRAP1) Antibody |
|
abx235721-100ug |
Abbexa |
100 ug |
EUR 610.8 |
|
|
 NGFRAP1 Immunizing Peptide |
|
MBS425539-01mg |
MyBiosource |
0.1mg |
EUR 225 |
 Rat NGFRAP1 shRNA Plasmid |
|
20-abx987406 |
Abbexa |
-
Ask for price
-
Ask for price
|
|
|
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) Human Protein BEX3 (NGFRAP1) |
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1-CSB-EP015781HU |
Cusabio |
-
Ask for price
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Ask for price
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Ask for price
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Ask for price
-
Ask for price
|
- 10ug
- 50ug
- 100ug
- 200ug
- 500ug
- 1MG
|
|
|
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Description: Recombinant Human Protein BEX3(NGFRAP1) expressed in E.coli |
Human Protein BEX3 (NGFRAP1) |
|
1-CSB-YP015781HU |
Cusabio |
-
Ask for price
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-
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|
- 10ug
- 50ug
- 100ug
- 200ug
- 500ug
- 1MG
|
|
|
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Description: Recombinant Human Protein BEX3(NGFRAP1) expressed in Yeast |
 Mouse NGFRAP1 shRNA Plasmid |
|
20-abx969345 |
Abbexa |
-
Ask for price
-
Ask for price
|
|
|
|
 Human NGFRAP1 shRNA Plasmid |
|
20-abx958923 |
Abbexa |
-
Ask for price
-
Ask for price
|
|
|
|
 (pORF)) Ngfrap1 ORF Vector (Rat) (pORF) |
|
ORF071295 |
ABM |
1.0 ug DNA |
EUR 607.2 |
 Recombinant Human NGFRAP1 Protein |
|
MBS8249499-001mg |
MyBiosource |
0.01mg |
EUR 295 |
Recombinant Human NGFRAP1 Protein |
|
MBS8249499-005mg |
MyBiosource |
0.05mg |
EUR 690 |
Recombinant Human NGFRAP1 Protein |
|
MBS8249499-05mg |
MyBiosource |
0.5mg |
EUR 2510 |
Recombinant Human NGFRAP1 Protein |
|
MBS8249499-5x05mg |
MyBiosource |
5x0.5mg |
EUR 11220 |
 (pORF)) NGFRAP1 ORF Vector (Human) (pORF) |
|
ORF007064 |
ABM |
1.0 ug DNA |
EUR 114 |
 (pORF)) Ngfrap1 ORF Vector (Mouse) (pORF) |
|
ORF051344 |
ABM |
1.0 ug DNA |
EUR 607.2 |
Ngfrap1 ORF Vector (Mouse) (pORF) |
|
ORF051345 |
ABM |
1.0 ug DNA |
EUR 607.2 |
Ngfrap1 ORF Vector (Mouse) (pORF) |
|
ORF051346 |
ABM |
1.0 ug DNA |
EUR 607.2 |
 Human NGFRAP1 knockout cell line |
|
ABC-KH10083 |
AcceGen |
1 vial |
Ask for price |
|
Description: Human NGFRAP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
 Human NGFRAP1 knockdown cell line |
|
ABC-KD10083 |
AcceGen |
1 vial |
Ask for price |
|
Description: Human NGFRAP1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
) Recombinant Rat Protein BEX3 (Ngfrap1) |
|
MBS1357599-002mgBaculovirus |
MyBiosource |
0.02mg(Baculovirus) |
EUR 1050 |
Recombinant Rat Protein BEX3 (Ngfrap1) |
|
MBS1357599-002mgEColi |
MyBiosource |
0.02mg(E-Coli) |
EUR 635 |
Recombinant Rat Protein BEX3 (Ngfrap1) |
|
MBS1357599-002mgYeast |
MyBiosource |
0.02mg(Yeast) |
EUR 805 |
Recombinant Rat Protein BEX3 (Ngfrap1) |
|
MBS1357599-01mgEColi |
MyBiosource |
0.1mg(E-Coli) |
EUR 735 |
Recombinant Rat Protein BEX3 (Ngfrap1) |
|
MBS1357599-01mgYeast |
MyBiosource |
0.1mg(Yeast) |
EUR 940 |
 - Rat nerve growth factor receptor (TNFRSF16) associated protein 1 (Ngfrap1), (10 ug)) Ngfrap1 (untagged ORF) - Rat nerve growth factor receptor (TNFRSF16) associated protein 1 (Ngfrap1), (10 ug) |
|
RN203570 |
Origene Technologies GmbH |
10 µg |
Ask for price |
) Recombinant Human Protein BEX3 (NGFRAP1) |
|
CSB-EP015781HU |
Cusabio |
1788 mg |
Ask for price |
Recombinant Human Protein BEX3 (NGFRAP1) |
|
CSB-EP015781HU-20ug |
Cusabio |
20ug |
Ask for price |
|
|
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Description: 1-111aa |
) Recombinant Human Protein BEX3(NGFRAP1) |
|
AP70585 |
SAB |
1mg |
EUR 1978 |
|
|
Recombinant Human Protein BEX3(NGFRAP1) |
|
AP72702 |
SAB |
each |
Ask for price |
|
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Recombinant Human Protein BEX3 (NGFRAP1) |
|
CSB-YP015781HU |
Cusabio |
5872 mg |
Ask for price |
Recombinant Human Protein BEX3 (NGFRAP1) |
|
CSB-YP015781HU-20ug |
Cusabio |
20ug |
Ask for price |
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Description: 1-111aa |
) Recombinant Mouse Protein BEX3 (Ngfrap1) |
|
MBS1344328-002mgBaculovirus |
MyBiosource |
0.02mg(Baculovirus) |
EUR 1045 |
Recombinant Mouse Protein BEX3 (Ngfrap1) |
|
MBS1344328-002mgEColi |
MyBiosource |
0.02mg(E-Coli) |
EUR 625 |
Recombinant Mouse Protein BEX3 (Ngfrap1) |
|
MBS1344328-002mgYeast |
MyBiosource |
0.02mg(Yeast) |
EUR 800 |
Recombinant Mouse Protein BEX3 (Ngfrap1) |
|
MBS1344328-01mgEColi |
MyBiosource |
0.1mg(E-Coli) |
EUR 725 |
Recombinant Mouse Protein BEX3 (Ngfrap1) |
|
MBS1344328-01mgYeast |
MyBiosource |
0.1mg(Yeast) |
EUR 935 |
 Rat Protein BEX3, NGFRAP1 ELISA Kit |
|
MBS9341088-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Rat Protein BEX3, NGFRAP1 ELISA Kit |
|
MBS9341088-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Rat Protein BEX3, NGFRAP1 ELISA Kit |
|
MBS9341088-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Rat Protein BEX3, NGFRAP1 ELISA Kit |
|
MBS9341088-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
) Recombinant Bovine Protein BEX3 (NGFRAP1) |
|
MBS1387516-002mgBaculovirus |
MyBiosource |
0.02mg(Baculovirus) |
EUR 1035 |
Recombinant Bovine Protein BEX3 (NGFRAP1) |
|
MBS1387516-002mgEColi |
MyBiosource |
0.02mg(E-Coli) |
EUR 610 |
Recombinant Bovine Protein BEX3 (NGFRAP1) |
|
MBS1387516-002mgYeast |
MyBiosource |
0.02mg(Yeast) |
EUR 790 |
Recombinant Bovine Protein BEX3 (NGFRAP1) |
|
MBS1387516-01mgEColi |
MyBiosource |
0.1mg(E-Coli) |
EUR 710 |
Recombinant Bovine Protein BEX3 (NGFRAP1) |
|
MBS1387516-01mgYeast |
MyBiosource |
0.1mg(Yeast) |
EUR 920 |
 Human Protein BEX3, NGFRAP1 ELISA Kit |
|
MBS9340067-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Human Protein BEX3, NGFRAP1 ELISA Kit |
|
MBS9340067-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Human Protein BEX3, NGFRAP1 ELISA Kit |
|
MBS9340067-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Human Protein BEX3, NGFRAP1 ELISA Kit |
|
MBS9340067-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
 Mouse Protein BEX3, NGFRAP1 ELISA Kit |
|
MBS9329921-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Mouse Protein BEX3, NGFRAP1 ELISA Kit |
|
MBS9329921-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Mouse Protein BEX3, NGFRAP1 ELISA Kit |
|
MBS9329921-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Collectively, we reveal β-NGF’s capability to advertise endochondral restore in a murine mannequin and uncover mechanisms that may serve to additional perceive the molecular switches that happen throughout cartilage to bone transformation.
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